AIP |
aryl hydrocarbon receptor interacting protein |
HGNC:358 |
11q13.3 |
hereditary cancer |
APC |
adenomatous polyposis coli |
HGNC:583 |
5q21-q22 |
hereditary cancer |
ATM |
ataxia telangiectasia mutated |
HGNC:795 |
11q22-q23 |
hereditary cancer |
AXIN2 |
axin 2 |
HGNC:904 |
17q23-q24 |
hereditary cancer |
BARD1 |
BRCA1 associated RING domain 1 |
HGNC:952 |
2q34-q35 |
hereditary cancer |
BMPR1A |
bone morphogenetic protein receptor, type IA |
HGNC:1076 |
10q22.3 |
hereditary cancer |
BRAF |
v-raf murine sarcoma viral oncogene homolog B1 |
HGNC:1097 |
7q34 |
hereditary cancer |
BRCA1 |
breast cancer 1, early onset |
HGNC:1100 |
17q21.31 |
hereditary cancer |
BRCA2 |
breast cancer 2, early onset |
HGNC:1101 |
13q12-q13 |
hereditary cancer |
BRIP1 |
BRCA1 interacting protein C-terminal helicase 1 |
HGNC:20473 |
17q22.2 |
hereditary cancer |
CASR |
calcium-sensing receptor |
HGNC:1514 |
3q21.1 |
hereditary cancer |
CDC73 |
cell division cycle 73 |
HGNC:16783 |
1q25 |
hereditary cancer |
CDH1 |
cadherin 1, type 1, E-cadherin (epithelial) |
HGNC:1748 |
16q22.1 |
hereditary cancer |
CDKN1A |
cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
HGNC:1784 |
6p21.1 |
hereditary cancer |
CDKN1B |
cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
HGNC:1785 |
12p13.1-p12 |
hereditary cancer |
CDKN2A |
cyclin-dependent kinase inhibitor 2A |
HGNC:1787 |
9p21 |
hereditary cancer |
CDKN2B |
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
HGNC:1788 |
9p21 |
hereditary cancer |
CDKN2C |
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
HGNC:1789 |
1p32.3 |
hereditary cancer |
CHEK1 |
checkpoint kinase 1 |
HGNC:1925 |
11q24.2 |
hereditary cancer |
CHEK2 |
checkpoint kinase 2 |
HGNC:16627 |
22q12.1 |
hereditary cancer |
DHFR |
dihydrofolate reductase |
HGNC:2861 |
5q11.2-q13.2 |
hereditary cancer |
ENG |
endoglin |
HGNC:3349 |
9q34.11 |
hereditary cancer |
EPCAM |
epithelial cell adhesion molecule |
HGNC:11529 |
2p21 |
hereditary cancer |
EXO1 |
exonuclease 1 |
HGNC:3511 |
1q42-q43 |
hereditary cancer |
FAM175A |
family with sequence similarity 175, member A |
HGNC:25829 |
4q21.23 |
hereditary cancer |
FH |
fumarate hydratase |
HGNC:3700 |
1q42.1 |
hereditary cancer |
FLCN |
folliculin |
HGNC:27310 |
17p11.2 |
hereditary cancer |
GALNT12 |
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12) |
HGNC:19877 |
9q22.33 |
hereditary cancer |
GNAS |
GNAS complex locus |
HGNC:4392 |
20q13.2-q13.3 |
hereditary cancer |
KRAS |
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
HGNC:6407 |
12p12.1 |
hereditary cancer |
MEN1 |
multiple endocrine neoplasia I |
HGNC:7010 |
11q13 |
hereditary cancer |
MET |
met proto-oncogene (hepatocyte growth factor receptor) |
HGNC:7029 |
7q31 |
hereditary cancer |
MGMT |
O-6-methylguanine-DNA methyltransferase |
HGNC:7059 |
10q26 |
hereditary cancer |
MLH1 |
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) |
HGNC:7127 |
3p22.3 |
hereditary cancer |
MLH3 |
mutL homolog 3 (E. coli) |
HGNC:7128 |
14q24.3 |
hereditary cancer |
MRE11A |
MRE11 meiotic recombination 11 homolog A (S. cerevisiae) |
HGNC:7230 |
11q21 |
hereditary cancer |
MSH2 |
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) |
HGNC:7325 |
2p21 |
hereditary cancer |
MSH3 |
mutS homolog 3 (E. coli) |
HGNC:7326 |
5q11-q12 |
hereditary cancer |
MSH6 |
mutS homolog 6 (E. coli) |
HGNC:7329 |
2p16 |
hereditary cancer |
MUTYH |
mutY homolog (E. coli) |
HGNC:7527 |
1p34.1 |
hereditary cancer |
NBN |
nibrin |
HGNC:7652 |
8q21-q24 |
hereditary cancer |
NF1 |
neurofibromin 1 |
HGNC:7765 |
17q11.2 |
hereditary cancer |
NF2 |
neurofibromin 2 (merlin) |
HGNC:7773 |
22q12.2 |
hereditary cancer |
NTRK1 |
neurotrophic tyrosine kinase, receptor, type 1 |
HGNC:8031 |
1q21-q22 |
hereditary cancer |
OGG1 |
8-oxoguanine DNA glycosylase |
HGNC:8125 |
3p26 |
hereditary cancer |
PALB2 |
partner and localizer of BRCA2 |
HGNC:26144 |
16p12.1 |
hereditary cancer |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
HGNC:8975 |
3q26.3 |
hereditary cancer |
PMS1 |
PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
HGNC:9121 |
2q31-q33 |
hereditary cancer |
PMS2 |
PMS2 postmeiotic segregation increased 2 (S. cerevisiae) |
HGNC:9122 |
7p22.1 |
hereditary cancer |
PRKAR1A |
protein kinase, cAMP-dependent, regulatory, type I, alpha |
HGNC:9388 |
17q23-q24 |
hereditary cancer |
PTCH1 |
patched 1 |
HGNC:9585 |
9q22.1-q31 |
hereditary cancer |
PTEN |
phosphatase and tensin homolog |
HGNC:9588 |
10q23 |
hereditary cancer |
PTPN11 |
protein tyrosine phosphatase, non-receptor type 11 |
HGNC:9644 |
12q24.1 |
hereditary cancer |
RAD50 |
RAD50 homolog (S. cerevisiae) |
HGNC:9816 |
5q23-q31 |
hereditary cancer |
RAD51 |
RAD51 recombinase |
HGNC:9817 |
15q15.1 |
hereditary cancer |
RAD51C |
RAD51 paralog C |
HGNC:9820 |
17q25.1 |
hereditary cancer |
RAD51D |
RAD51 paralog D |
HGNC:9823 |
17q11 |
hereditary cancer |
RET |
ret proto-oncogene |
HGNC:9967 |
10q11.2 |
hereditary cancer |
SDHB |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
HGNC:10681 |
1p36.1-p35 |
hereditary cancer |
SDHD |
succinate dehydrogenase complex, subunit D, integral membrane protein |
HGNC:10683 |
11q23 |
hereditary cancer |
SMAD4 |
SMAD family member 4 |
HGNC:6770 |
18q21.1 |
hereditary cancer |
SPRED1 |
sprouty-related, EVH1 domain containing 1 |
HGNC:20249 |
15q14 |
hereditary cancer |
STK11 |
serine/threonine kinase 11 |
HGNC:11389 |
19p13.3 |
hereditary cancer |
TGFB1 |
transforming growth factor, beta 1 |
HGNC:11766 |
19q13.1 |
hereditary cancer |
TP53 |
tumor protein p53 |
HGNC:11998 |
17p13.1 |
hereditary cancer |
TP73 |
tumor protein p73 |
HGNC:12003 |
1p36.3 |
hereditary cancer |
TYMS |
thymidylate synthetase |
HGNC:12441 |
18p11.31-p11.21 |
hereditary cancer |
UIMC1 |
ubiquitin interaction motif containing 1 |
HGNC:30298 |
5q35.2 |
hereditary cancer |
VHL |
von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
HGNC:12687 |
3p25.3 |
hereditary cancer |
XRCC2 |
X-ray repair complementing defective repair in Chinese hamster cells 2 |
HGNC:12829 |
7q36 |
hereditary cancer |
XRCC3 |
X-ray repair complementing defective repair in Chinese hamster cells 3 |
HGNC:12830 |
14q32.3 |
hereditary cancer |