Gene symbolGene nameDisease panel
VCLvinculinheart
TXNRD2thioredoxin reductase 2heart
TTRtransthyretinheart
TTNtitinheart: Cardiomyopathy, FDC
TRDNtriadinheart
TPM1tropomyosin 1 (alpha)heart: Cardiomyopathy, FDC, HCM
TNNT2troponin T type 2 (cardiac)heart: Cardiomyopathy, FDC, HCM
TNNI3troponin I type 3 (cardiac)heart: Cardiomyopathy, FDC, HCM
TNNC1troponin C type 1 (slow)heart: Cardiomyopathy, FDC
TMPOthymopoietinheart
TMEM43transmembrane protein 43heart: Cardiomyopathy, ARVC
TGFBR2transforming growth factor, beta receptor II (70/80kDa)heart: Thoracic aorta dilation
TGFBR1transforming growth factor, beta receptor 1heart: Thoracic aorta dilation
TGFB3transforming growth factor, beta 3heart
TCAPtitin-capheart: Cardiomyopathy, FDC, HCM
TBX5T-box 5heart
TBX1T-box 1heart
TAZtafazzinheart: Cardiomyopathy, FDC
SNTA1syntrophin, alpha 1heart: Primary hereditary arrythmia, LQTS
SMAD3SMAD family member 3heart
SLC8A1solute carrier family 8 (sodium/calcium exchanger), member 1heart
SLC25A4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4heart
SGCDsarcoglycan, delta (35kDa dystrophin-associated glycoprotein)heart: Cardiomyopathy, FDC, HCM
SCN5Asodium channel, voltage-gated, type V, alpha subunitheart: Primary hereditary arrythmia, , LQTS, BrS, ERS, PCCD
SCN4Bsodium channel, voltage-gated, type IV, beta subunitheart: Primary hereditary arrythmia, LQTS, BrS
SCN3Bsodium channel, voltage-gated, type III, beta subunitheart: Primary hereditary arrythmia, BrS
SCN1Bsodium channel, voltage-gated, type I, beta subunitheart: Primary hereditary arrythmia, BrS
RYR2ryanodine receptor 2 (cardiac)heart: Cardiomyopathy, ARVC
RBM20RNA binding motif protein 20heart: DCM
RANGRFRAN guanine nucleotide release factorheart
RAF1v-raf-1 murine leukemia viral oncogene homolog 1heart: Cardiomyopathy, HCM
PTPN11protein tyrosine phosphatase, non-receptor type 11heart: Cardiomyopathy, HCM
PSEN2presenilin 2heart
PSEN1presenilin 1heart
PRKAG2protein kinase, AMP-activated, gamma 2 non-catalytic subunitheart: Cardiomyopathy, HCM
PLNphospholambanheart: Cardiomyopathy, FDC, HCM
PKP2plakophilin 2heart: Cardiomyopathy
PDLIM3PDZ and LIM domain 3heart
PCSK9proprotein convertase subtilisin/kexin type 9heart
NPPAnatriuretic peptide Aheart: Cardiomyopathy, FDC
NOTCH1notch 1heart
NKX2-5NK2 homeobox 5heart
NEXNnexilin (F actin binding protein)heart
NEBLnebuletteheart
MYPNmyopalladinheart
MYOZ2myozenin 2heart
MYOM1myomesin 1heart
MYLK2myosin light chain kinase 2heart
MYL3myosin, light chain 3, alkali; ventricular, skeletal, slowheart: Cardiomyopathy, FDC, HCM
MYL2myosin, light chain 2, regulatory, cardiac, slowheart: Cardiomyopathy, FDC, HCM
MYH7myosin, heavy chain 7, cardiac muscle, betaheart: Cardiomyopathy, FDC, HCM
MYH6myosin, heavy chain 6, cardiac muscle, alphaheart: Cardiomyopathy, FDC, HCM
MYBPC3myosin binding protein C, cardiacheart : Cardiomyopathy, FDC, HCM
MTHFRmethylenetetrahydrofolate reductase (NAD(P)H)heart
LMNAlamin A/Cheart: Primary hereditary arrythmia, PCCD
LDLRlow density lipoprotein receptorheart
LDB3LIM domain binding 3heart
LAMP2lysosomal-associated membrane protein 2heart
LAMA4laminin, alpha 4heart
KLF10Kruppel-like factor 10heart
KCNQ1potassium voltage-gated channel, KQT-like subfamily, member 1heart: Primary hereditary arrythmia, LQTS, SQTS
KCNJ8potassium inwardly-rectifying channel, subfamily J, member 8heart
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 5heart
KCNJ2potassium inwardly-rectifying channel, subfamily J, member 2heart: Primary hereditary arrythmia, LQTS, SQTS
KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2heart: Primary hereditary arrythmia, LQTS
KCNE3potassium voltage-gated channel, Isk-related family, member 3heart
KCNE2potassium voltage-gated channel, Isk-related family, member 2heart: Primary hereditary arrythmia, BrS
KCNE1LKCNE1-likeheart: Primary hereditary arrythmia, LQTS
KCNE1potassium voltage-gated channel, Isk-related family, member 1heart: Primary hereditary arrythmia, LQTS, BrS
KCND3potassium voltage-gated channel, Shal-related subfamily, member 3heart: Primary hereditary arrythmia
KCNA5potassium voltage-gated channel, shaker-related subfamily, member 5heart
JUPjunction plakoglobinheart: Cardiomyopathy
JPH2junctophilin 2heart: Cardiomyopathy, HCM
JAG1jagged 1heart
ILKintegrin-linked kinaseheart
HCN4hyperpolarization activated cyclic nucleotide-gated potassium channel 4heart
GPD1Lglycerol-3-phosphate dehydrogenase 1-likeheart
GLAgalactosidase, alphaheart
GJA5gap junction protein, alpha 5, 40kDaheart
GATA4GATA binding protein 4heart
FXNfrataxinheart
FKTNfukutinheart
FHL1four and a half LIM domains 1heart
FBN2fibrillin 2heart
FBN1fibrillin 1heart: Thoracic aorta dilation
EYA4eyes absent homolog 4 (Drosophila)heart
EMDemerinheart
DTNAdystrobrevin, alphaheart
DSPdesmoplakinheart: Cardiomyopathy
DSG2desmoglein 2heart: Cardiomyopathy, ARVC
DSC2desmocollin 2heart: Cardiomyopathy, ARVC
DMDdystrophinheart: Cardiomyopathy, FDC
DESdesminheart: Cardiomypathy, FDC
CTF1cardiotrophin 1heart
CSRP3cysteine and glycine-rich protein 3 (cardiac LIM protein)heart: Cardiomyopathy, FDC
CRYABcrystallin, alpha Bheart
CBScystathionine-beta-synthaseheart
CAV3caveolin 3heart: Primary hereditary arrythmia, LQTS
CASQ2calsequestrin 2 (cardiac muscle)heart: Primary hereditary arrythmia, CPVT
CALR3calreticulin 3heart
CALM3calmodulin 3 (phosphorylase kinase, delta)heart: Primary hereditary arrythmia, CPVT
CALM2calmodulin 2 (phosphorylase kinase, delta)heart: Primary hereditary arrythmia, CPVT
CALM1calmodulin 1 (phosphorylase kinase, delta)heart: Primary hereditary arrythmia, CPVT
CACNB2calcium channel, voltage-dependent, beta 2 subunitheart: Primary hereditary arrythmia, SQTS, BrS, ERS
CACNA2D1calcium channel, voltage-dependent, alpha 2/delta subunit 1heart: Primary hereditary arrythmia, BrS
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunitheart: Primary hereditary arrythmia, LQTS, SQTS, BrS, ERS
BAG3BCL2-associated athanogene 3heart: Cardiomyopathy, FDC
APOBapolipoprotein Bheart
ANKRD1ankyrin repeat domain 1 (cardiac muscle)heart:Cardiomyopathy, DCM, HCM
ANK2ankyrin 2, neuronalheart: Primary hereditary arrythmia, LQTS
AKAP9A kinase (PRKA) anchor protein 9heart: Primary hereditary arrythmia, LQTS
ACTN2actinin, alpha 2heart
ACTC1actin, alpha, cardiac muscle 1heart: cardiomyopathy, FDC, HCM
ACTA2actin, alpha 2, smooth muscle, aortaheart
ABCC9ATP-binding cassette, sub-family C (CFTR/MRP), member 9heart:primary hereditary arrythmia, SQTS, ERS