Cancer subpanels valid from 2021-04-20

 

Breastcancer v2
BRCA1, BRCA2, PALB2, PTEN, STK11,TP53

Ovarian cancer v3
BRCA1, BRCA2, BRIP1, EPCAM**, MLH1, MSH2, MSH6, PMS2*, RAD51C, RAD51D, STK11

Other breast/ovarian cancer genes v3
ABRAXAS1, ATM, BARD1, CHEK2, FANCM, GEN1, MRE11, NBN, PIK3CA, PPM1D, RINT1, XRCC2

Colorectal Cancer and Polyposis v1
APC, AXIN2, BMPR1A, EPCAM**, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS1, PMS2*, POLD1, POLE, PTEN, RNF43, SCG5**, SMAD4, STK11

Lynch syndrome v2
EPCAM**, MLH1, MSH2, MSH6, PMS2*

FAP og MAP v1
APC, MUTYH

Multiple Endocrine Neoplasia v3
AIP, AP2S1, CASR, CDC73, CDKN1A, CDKN1B, CDKN2B, CDKN2C, GNA11, GNAS, MEN1, NTRK1, PRKAR1A, RET, SDHB, SDHC, SDHD, VHL

Neurofibromatosis v1
NF1, NF2, SPRED1

Kidney cancer v3
BAP1, CDKN2B, FH, FLCN, MET, MITF, PTEN, SDHA, SDHAF2, SDHB, SDHC, VHL

Gorlin syndrome v3
PTCH1, PTCH2, SUFU

Li-Fraumeni syndrome v1
TP53

Peutz-Jegher syndrome v1
STK11

HDGC, Hereditary Diffuse Gastric Cancer v2
CDH1, CTNNA1

Maligne melanome v1
ACD, BAP1, BRCA2, CDK4, CDKN2A, MITF, POLE, POT1, TERF2IP, TERT

Pancreas cancer v1
BRCA1, BRCA2, CDKN2A, EPCAM**, MLH1, MSH2, MSH6, PALB2, PMS2*, PRSS1, STK11

Schwannomatosis v1
SMARCB1, LZTR1, NF1, NF2

* MLPA part of analysis **Only CNV analysis