Research at MOMA - Overview

 

Translational Research

Translational research at MOMA  integrates clinical specimens and clinical studies with in vitro studies and molecular models of colon, bladder and prostate cancer diseases. MOMA is manifesting its international position by conducting translational research at a competitive level.

Comprehensive tissue banks including detailed clinical follow-up are established and maintained by MOMA in close cooperation with clinicians treating cancer patients.

 

Research Aims

Molecular classification of patients in relation to disease stage, prognosis, outcome and treatment and insight into molecular pathways in subgroups of patients are desired.
Bioinformatic modelling and large databases help to understand the importance of our molecular findings.
 

Modern technology

MOMA uses advanced techniques and equipment for investigating gene expression, genomic instability, genomic variation, several RNA species and laser microdissected tissues, and for functional classification of early molecular changes and pathways.

MOMA has modern laboratory facilities and computer equipment. See a list of equipment

 

 

Current Research Network and Large Projects

DCCC Danish circulating tumor DNA network (DCCC ctDNA) (2019-)

NorDCaP - Nordic Implementation of Personalised Prostate Cancer Diagnostics (2019-)

PRIMA - Early and accurate detection of prostate cancer in general practice (2018-)

IMPROVE - Implementing Non-invasive Circulating Tumor DNA Analysis to Optimize the Operative and Postoperative Treatment for Patients With Colorectal Cancer (2018-2025)

IMPROVE-IT - Intervention Trial Implementing Non-invasive Circulating Tumor DNA Analysis to Optimize the Operative and Postoperative Treatment for Patients With Colorectal Cancer

"Individualized monitoring of cancer by deep sequencing of circulating tumor DNA in patients with advanced bladder cancer "(2017-)

PROCARIS - A new strategy to prevent overdiagnosis and overtreatment of non-aggressive prostate cancer in the aging male population (2016-)

PAGER - Analyzis of personal genomic rearrangements for surveillance of patients with bladder cancer (2013-)

OPRA - Oncology Precision Medicine Project Aarhus (2017-)

NEXT - Danish study of personalised cancer therapy based on tumor genetics (2017-)

""Early detection of recurrence and more curative therapy for colon cancer patients" (2016-2020)

PanCancer Analysis of Whole Genomes (PCAWG) Project (2015-)

Long non-coding RNAs as biomarkers and novel drivers of human bladder cancer (2014-)

Research Groups at MOMA

Bladder Cancer Group (Lars Dyrskjøt)

Colon Cancer Group (Claus Lindbjerg)

Prostate Cancer Group (Karina Dalsgaard Sørensen)

Medical Research Group (Claus Gravholt)

Bioinformatics Groups: